The Vermillion, often referred to as the Vermillion warriors, are the pure first-generation progeny of the Great Devourer, appearing as masses of snakes that can merge into humanoid- snakelike forms. With armor forged by Ray and Maya and the leadership of Krux and Acronix, the Vermillion's main agenda is to consume everything in their path, much like their progenitor.

Following the Battle for All of Time, Krux had been breeding them in the Vermillion Swamps, so he could oversee their invasion in forty years while waiting for Acronix to return.

The Vermillion commanders Machia, Raggmunk, and Blunck were selected by Krux as the strongest and most cunning of their species. They are capable of controlling the other Vermillion warriors through a hive mind until Acronix and Krux fired the Vermillion commanders and used the helmets of Blunck and Raggmunk to control the Vermillion warriors themselves.

With control of the Vermillion, the twins telepathically smashed the rest of the Vermillion warriors into their component snakes, which were absorbed by the Iron Doom. Under the twins' orders, the Vermillion snakes ultimately gave life to the machine. Eventually, it would become lost in time after Wu ripped out the Reversal Time Blade from the Iron Doom's time apparatus, leaving the Time Twins and their Vermillion hordes stuck in the Temporal vortex.