The Pyro Vipers are an ancient Hypnobrai Serpentine tribe revived and currently led by Aspheera to aid her in her conquest of Ninjago. Formerly, they lived in the Desert of Doom and were ruled by Mambo V. After Wu and Garmadon used the Scrolls of Forbidden Spinjitzu to stop Aspheera when she tried to overthrow Mambo V, she was sentenced to be locked in the pyramid till her sins were forgotten.

Eventually, the tribe died off and their sarcophagi remained inside the pyramid. When the ninja explored the pyramid and unwittingly released Aspheera, the pyramid's destruction revived and freed the rest of the Pyro Vipers. They gained the power of fire from the lava which released them from their sarcophagi.

Their goal was to exact revenge upon the boy who imprisoned Aspheera long ago by banishing him to the Never-Realm. Aspheera and the Pyro Vipers raided the Monastery of Spinjitzu. They were all frozen by Zane. However, Aspheera banished him to the Never-Realm, an event which caused him to become the Ice Emperor.